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Título : Aspergilosis broncopulmonar alérgica, una complicación del paciente con fibrosis quística : reporte de dos casos y revisión de la literatura
Otros títulos : Allergic bronchopulmonary aspergillosis, a complication of patients with cystic fibrosis : Report of two cases and review of the literature
Autor : Ballesteros Calderón, Alicia Lucía
Morales Múnera, Olga Lucía
Roya Pabón, Claudia Liliana
metadata.dc.subject.*: Aspergilosis Broncopulmonar Alérgica
Asteroide
Fibrosis Quística
Fecha de publicación : 2012
Editorial : Universidad de Antioquia, Facultad de Medicina
Citación : Ballesteros Calderón AL, Morales Múnera OL, Roya Pabón CL. Aspergilosis broncopulmonar alérgica, una complicación del paciente con fibrosis quística: reporte de dos casos y revisión de la literatura. Iatreia. 2012 Ene-Mar;25(1):65 - 74.
Resumen : Allergic bronchopulmonary aspergillosis (ABPA) is a lung disease resulting from hypersensitivity to Aspergillus, which leads to impaired mucociliary clearance, mucus impaction with obstruction of the airway, and pulmonary infiltration. Clinically it is characterized by dyspnea, wheezing, fever, malaise, brown or black expectoration, and poor clinical response to the standard therapy for exacerbations in patients with chronic lung disease. In patients with cystic fibrosis (CF) it may be difficult to establish the diagnosis of ABPA due to the overlapping of clinical, radiological and immunological features and to the high frequency of pulmonary bacterial infections. Therefore, annual monitoring of these patients is recommended by measuring the level of total immunoglobulin E (IgE); according to its result and to the clinical context, the diagnosis and treatment of ABPA with steroids should be considered. Such treatment leads to improvement of symptoms, lung function, quality of life and prognosis. We report two pediatric patients diagnosed with CF who were difficult to control; the diagnosis of ABPA was established and their pulmonary symptoms improved with the use of steroids.
metadata.dc.identifier.eissn: 2011-7965
ISSN : 0121-0793
Aparece en las colecciones: Instituto de Investigaciones Médicas

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