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dc.contributor.authorValle Agudelo, Gustavo del-
dc.contributor.authorEstrada, Ricardo-
dc.contributor.authorValderrama Hernández, Rafael-
dc.contributor.authorRobles, Abel-
dc.contributor.authorOsorio Gutiérrez, Raúl Guillermo-
dc.contributor.authorGutiérrez Gutiérrez, José María-
dc.contributor.authorOtero Patiño, Rafael-
dc.contributor.authorGiraldo, César Augusto-
dc.contributor.authorNúñez Rangel, Vitelbina-
dc.date.accessioned2022-01-12T16:23:17Z-
dc.date.available2022-01-12T16:23:17Z-
dc.date.issued1997-
dc.identifier.citationOtero R, Núñez V, Gutiérrez J, Robles A, Estrada R, Osorio R, Del-Valle G, et al. Neutralizing capacity of a new monovalent anti-Bothrops atrox antivenom: comparison with two commercial antivenoms. Braz J Med Biol Res1997;30(3):375-9.spa
dc.identifier.issn0100-879X-
dc.identifier.urihttp://hdl.handle.net/10495/25225-
dc.description.abstractABSTRACT: Three horse-derived antivenoms were tested for their ability to neu-tralize lethal, hemorrhagic, edema-forming, defibrinating and myotoxicactivitiesinduced by the venom of Bothrops atrox from Antioquia andChocó (Colombia). The following antivenoms were used: a) polyva-lent (crotaline) antivenom produced by Instituto Clodomiro Picado(Costa Rica), b) monovalent antibothropic antivenom produced byInstituto Nacional de Salud-INS (Bogotá), and c) a new monovalentanti-B. atrox antivenom produced with the venom of B. atrox fromAntioquia and Chocó. The three antivenoms neutralized alltoxicactivitiestested albeit with different potencies. The new monovalentanti-B. atrox antivenomshowed the highest neutralizing ability againstedema-forming and defibrinating effects of B. atrox venom (41 ± 2and 100 ± 32 μl antivenom/mgvenom, respectively), suggesting thatitshould be usefulin the treatment of B. atrox envenomation inAntioquia and Chocó.spa
dc.format.extent5spa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherAssociação Brasileira de Divulgação Científicaspa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersionspa
dc.rightsinfo:eu-repo/semantics/openAccessspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/2.5/co/*
dc.titleNeutralizing capacity of a new monovalent anti-Bothrops atrox antivenom: comparison with two commercial antivenomsspa
dc.typeinfo:eu-repo/semantics/articlespa
dc.publisher.groupToxinología Alternativas Terapéuticas y Alimentariasspa
dc.publisher.groupGrupo de Entomología Médica de la Universidad de Antioquiaspa
dc.identifier.doi10.1590/S0100-879X1997000300011-
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2spa
dc.identifier.eissn1414-431X-
oaire.citationtitleBrazilian Journal of Medical and Biological Researchspa
oaire.citationstartpage375spa
oaire.citationendpage379spa
oaire.citationvolume30spa
oaire.citationissue3spa
dc.rights.creativecommonshttps://creativecommons.org/licenses/by/4.0/spa
dc.publisher.placeSão Paulo, Brasilspa
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa
dc.type.redcolhttps://purl.org/redcol/resource_type/ARTspa
dc.type.localArtículo de investigaciónspa
dc.subject.decsBothrops-
dc.subject.decsVenenos de Serpiente-
dc.subject.decsSnake Venoms-
dc.subject.decsNeutralización-
dc.subject.decsNeutralization-
dc.subject.lembAntioquia (Colombia)-
dc.subject.lembChocó (Colombia)-
dc.description.researchgroupidCOL0014476spa
dc.description.researchgroupidCOL0008109spa
dc.relation.ispartofjournalabbrevBraz. J. Med. Biol. Res.spa
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