Por favor, use este identificador para citar o enlazar este ítem:
https://hdl.handle.net/10495/26760| Título : | Meta-analysis of genome-wide linkage scans of attention deficit hyperactivity disorder |
| Autor : | Zhou, Kaixin Dempfle, Astrid Arcos Burgos, Oscar Mauricio Bakker, Steven Banaschewski, Tobias Biederman, Joseph Buitelaar, Jan Castellanos, Francisco Xavier Doyle, Alysa Ebstein, Richard Ekholm, Jenny Forabosco, Paola Franke, Barbara Freitag, Christine Friedel, Susann Gill, Michael Hebebrand, Johannes Hinney, Anke Jacob, Christian Lesch, Klaus Peter Loo, Sandra Lopera Restrepo, Francisco Javier McCracken, James McGough, James Meyer, Jobst Mick, Eric Miranda Casas, Ana Muenke, Maximilian Mulas Delgado, Fernando Nelson, Stanley F. Nguyen, Trang Oades, Robert Ogdie, Matthew Palacio Ortiz, Juan David Pineda Álvarez, Daniel Reif, Andreas Renner, Tobias Roeyers, Herbert Romanos, Marcel Rothenberger, Aribert Schäfer, Helmut Sergeant, Joseph Sinke, Richard Smalley, Susan Sonugac Barke, Edmund Steinhausen, Hans Christoph Van der Meulen, Emma Walitza, Susanne Warnke, Andreas Lewis, Cathryn Faraone, Stephen Asherson, Philip |
| metadata.dc.subject.*: | Attention Deficit Disorder with Hyperactivity Trastorno por Déficit de Atención con Hiperactividad Genetic Linkage Ligamiento Genético Chromosome Mapping Mapeo Cromosómico Chromosomes, Human, Pair 16 Cromosomas Humanos Par 16 Genome, Human Genoma Humano European Continental Ancestry Group Grupo de Ascendencia Continental Europea |
| Fecha de publicación : | 2008 |
| Editorial : | Wiley-Blackwell |
| Citación : | Zhou, K., Dempfle, A., Arcos, M., Bakker, S., Banaschewski, T., Biederman, J., Buitelaar, J., Castellanos, F. X., Doyle, A., Ebstein, R. P., Ekholm, J., Forabosco, P., Franke, B., Freitag, C., Friedel, S., Gill, M., Hebebrand, J., Hinney, A., Jacob, C., Lesch, K. P., … Asherson, P. (2008). Meta-analysis of genome-wide linkage scans of attention deficit hyperactivity disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 147B(8), 1392–1398. https://doi.org/10.1002/ajmg.b.30878 |
| Resumen : | ABSTRACT: Genetic contribution to the development of attention deficit hyperactivity disorder (ADHD) is well established. Seven independent genome-widelinkage scans have been performed to map loci that increase the risk for ADHD. Although sig-nificant linkage signals were identified in some ofthe studies, there has been limited replications between the various independent datasets. The current study gathered the results from all sevenof the ADHD linkage scans and performed a Genome Scan Meta Analysis (GSMA) to identify the genomic region with most consistent linkage evidence across the studies. Genome-wide signifi-cant linkage (PSR¼0.00034,POR¼0.04) was identi-fied on chromosome 16 between 64 and 83 Mb. In addition there are nine other genomic regions from the GSMA showing nominal or suggestive evidence of linkage. All these linkage results maybe informative and focus the search for novel ADHD susceptibility genes. |
| metadata.dc.identifier.eissn: | 1552-485X |
| ISSN : | 1552-4841 |
| metadata.dc.identifier.doi: | 10.1002/ajmg.b.30878 |
| Aparece en las colecciones: | Artículos de Revista en Ciencias Exactas y Naturales |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| ArcosOscar_2008_Meta-Analisis-Genoma.pdf | Artículo de revisión | 337.5 kB | Adobe PDF | Visualizar/Abrir |
Este ítem está sujeto a una licencia Creative Commons Licencia Creative Commons
