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https://hdl.handle.net/10495/32011
Título : | Sputum induction is a safe procedure to use in prisoners and MGIT is the best culture method to diagnose tuberculosis in prisons: a cohort study |
Autor : | Rueda Vallejo, Zulma Vanessa López López, Lucelly Marín Pineda, Diana Marcela Vélez Giraldo, Lázaro Agustín Arbeláez Montoya, María Patricia |
metadata.dc.subject.*: | Tuberculosis Pulmonar Tuberculosis, Pulmonary Prisioneros Prisoners Prisiones Prisons Técnicas Bacteriológicas Bacteriological Techniques Benzofenoneido Benzophenoneidum Esputo Sputum Estudios de Cohortes Cohort Studies |
Fecha de publicación : | 2015 |
Editorial : | Elsevier International Society for Infectious Diseases |
Citación : | Rueda ZV, López L, Marín D, Vélez LA, Arbeláez MP. Sputum induction is a safe procedure to use in prisoners and MGIT is the best culture method to diagnose tuberculosis in prisons: a cohort study. Int J Infect Dis. 2015 Apr;33:82-8. doi: 10.1016/j.ijid.2015.01.004. |
Resumen : | ABSTRACT: Objectives: To evaluate the concordance and safety of induced sputum (IS) and spontaneous sputum (SS), and estimate concordance and time to detection of M. tuberculosis between Lowenstein-Jensen (LJ), thin-layer agar (TLA), and the Mycobacteria Growth Indicator Tube system (MGIT). Methods: This was a cohort study. Prisoners with pulmonary tuberculosis (PTB) were followed for 2 years. At baseline and every follow-up visit, three sputum samples were taken on consecutive days (one IS and two SS) and adverse events occurring before, during, and 30 min after IS were registered. All sputum samples were stained with auramine and cultured in LJ, TLA (to test resistance), and MGIT. Results: Five hundred eighty-six IS and 532 SS were performed on 64 PTB patients. Breathlessness (1.6%), cough (1.2%), hemoptysis (0.3%), and cyanosis (0.2%) were the only complications. Concordance between IS and SS was 0.78 (95% confidence interval 0.69-0.87); 11 positive cultures from IS samples were negative in SS, and 11 positive cultures from SS samples were negative in IS. One hundred seventy-eight cultures were positive by any technique: MGIT 95%, LJ 73%, and TLA 57%. Time to detection of M. tuberculosis in LJ, TLA, and MGIT was 31, 18, and 11 days, respectively. Conclusions: The IS procedure is safe in prisons. The MGIT system is better and faster than LJ and TLA in the diagnosis of M. tuberculosis. |
metadata.dc.identifier.eissn: | 1878-3511 |
ISSN : | 1201-9712 |
metadata.dc.identifier.doi: | 10.1016/j.ijid.2015.01.004. |
Aparece en las colecciones: | Artículos de Revista en Ciencias Médicas |
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Fichero | Descripción | Tamaño | Formato | |
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RuedaZulma_2015_SputumPrisonersTuberculosis.pdf | Artículo de investigación | 797.55 kB | Adobe PDF | Visualizar/Abrir |
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