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dc.contributor.authorPabón Vidal, Adriana Lucía-
dc.contributor.authorBlair Trujillo, Silvia-
dc.contributor.authorZuleta, Margarita-
dc.contributor.authorCarmona Fonseca, Jaime-
dc.contributor.authorSáez Vega, Jairo Antonio-
dc.date.accessioned2022-11-13T19:31:26Z-
dc.date.available2022-11-13T19:31:26Z-
dc.date.issued2003-
dc.identifier.citationPabón A, Blair S, Carmona J, Zuleta M, Saez J. Evaluation of the mutagenicity of antimalarial products isolated from Solanum nudum (Solanaceae). Pharmazie. 2003 Apr;58(4):263-7.spa
dc.identifier.issn0031-7144-
dc.identifier.urihttps://hdl.handle.net/10495/32014-
dc.description.abstractABSTRACT: Diosgenone is a major component of the hexane extract from the plant Solanum nudum (Solanaceae). The products from degraded and acetylated diosgenone that showed in vitro antimalarial activity against the FCB-2 strain of Plasmodium falciparum and methanol, dichloromethane and ethereal extracts of Solanum nudum were tested for their mutagenic activity using the Ames test with the TA-97a, TA-98, TA-100 and TA-102 strains of Salmonella typhimurium. These compounds were not mutagenic at the tested concentrations.spa
dc.format.extent5spa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherGovi-Verlag Pharmazautischer Verlagspa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersionspa
dc.rightsinfo:eu-repo/semantics/openAccessspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/*
dc.titleEvaluation of the Mutagenicity of Antimalarial products isolated from Solanum nudum (Solanaceae)spa
dc.typeinfo:eu-repo/semantics/articlespa
dc.publisher.groupGrupo Malariaspa
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2spa
oaire.citationtitleDie Pharmaziespa
oaire.citationstartpage263spa
oaire.citationendpage267spa
oaire.citationvolume58spa
oaire.citationissue4spa
dc.rights.creativecommonshttps://creativecommons.org/licenses/by-nc-nd/4.0/spa
dc.publisher.placeBerlín, Alemaniaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa
dc.type.redcolhttps://purl.org/redcol/resource_type/ARTspa
dc.type.localArtículo de investigaciónspa
dc.subject.decsAcetilación-
dc.subject.decsAcetylation-
dc.subject.decsSustitución de Aminoácidos-
dc.subject.decsAmino Acid Substitution-
dc.subject.decsAntimaláricos-
dc.subject.decsAntimalarials-
dc.subject.decsPruebas de Mutagenicidad-
dc.subject.decsMutagenicity Tests-
dc.subject.decsExtractos Vegetales-
dc.subject.decsPlant Extracts-
dc.subject.decsSalmonella typhimurium-
dc.subject.decsCompuestos de Espiro-
dc.subject.decsSpiro Compounds-
dc.description.researchgroupidCOL0007524spa
dc.relation.ispartofjournalabbrevPharmazie.spa
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