1. Repositorio Institucional Universidad de Antioquia
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dc.contributor.authorMiranda Angulo, Ana Lucia-
dc.contributor.authorLee, Daniel A.-
dc.contributor.authorBedont, Joseph L.-
dc.contributor.authorPak, Thomas-
dc.contributor.authorWang, Hong-
dc.contributor.authorSong, Juan-
dc.contributor.authorTakiar, Vani-
dc.contributor.authorCharubhumi, Vanessa-
dc.contributor.authorBalordi, Francesca-
dc.contributor.authorTakebayashi, Hirohide-
dc.contributor.authorAja, Susan-
dc.contributor.authorFord, Eric-
dc.contributor.authorFishell, Gordon-
dc.contributor.authorBlackshaw, Seth-
dc.date.accessioned2023-10-02T14:26:15Z-
dc.date.available2023-10-02T14:26:15Z-
dc.date.issued2012-
dc.identifier.citationLee DA, Bedont JL, Pak T, Wang H, Song J, Miranda-Angulo A, Takiar V, Charubhumi V, Balordi F, Takebayashi H, Aja S, Ford E, Fishell G, Blackshaw S. Tanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche. Nat Neurosci. 2012 Mar 25;15(5):700-2. doi: 10.1038/nn.3079. PMID: 22446882; PMCID: PMC3380241.spa
dc.identifier.issn1097-6256-
dc.identifier.urihttps://hdl.handle.net/10495/36725-
dc.description.abstractABSTRACT:Adult hypothalamic neurogenesis has been recently reported, but the cell of origin and function of these newborn neurons are unknown. We utilize genetic fate mapping to show that median eminence tanycytes generate newborn neurons; blocking this neurogenesis alters weight and metabolic activity in adult mice. These findings describe a previously unreported neurogenic niche within the mammalian hypothalamus with important implications for metabolism.spa
dc.format.extent11spa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherNature Researchspa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersionspa
dc.rightsinfo:eu-repo/semantics/openAccessspa
dc.rights.urihttp://creativecommons.org/licenses/by/2.5/co/*
dc.titleTanycytes of the hypothalamic median eminence form a diet-responsive neurogenic niche.spa
dc.typeinfo:eu-repo/semantics/articlespa
dc.publisher.groupGrupo de Investigación en Psiquiatría GIPSIspa
dc.identifier.doi10.1038/nn.3079-
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2spa
dc.identifier.eissn1546-1726-
oaire.citationtitleNature Neurosciencespa
oaire.citationstartpage1spa
oaire.citationendpage11spa
oaire.citationvolume15spa
oaire.citationissue5spa
dc.rights.creativecommonshttps://creativecommons.org/licenses/by/4.0/spa
dc.publisher.placeNueva York, Estados Unidosspa
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa
dc.type.redcolhttps://purl.org/redcol/resource_type/ARTspa
dc.type.localArtículo de investigaciónspa
dc.subject.decsNeurogénesis-
dc.subject.decsHipotálamo-
dc.subject.decsHypothalamus-
dc.subject.decsPeso corporal-
dc.subject.decsBody Weight-
dc.subject.decsBromodesoxiuridina-
dc.subject.decsBromodeoxyuridine-
dc.subject.decsDieta alta en grases-
dc.subject.decsDiet hight fat-
dc.subject.decsEminencia Media-
dc.subject.decsMedian Eminence-
dc.subject.decsRatones endogámicos C57BL-
dc.subject.decsMice, Inbred C57BL-
dc.subject.decsReceptores de estrógeno-
dc.subject.decsReceptors, Estrogen-
dc.subject.decsTamoxifeno-
dc.subject.decsTamoxifen-
dc.description.researchgroupidCOL0029147spa
dc.relation.ispartofjournalabbrevNat. Neurosci.spa
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