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https://hdl.handle.net/10495/38198Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.contributor.author | Arango Acosta, Gabriel Jaime | - |
| dc.contributor.author | Jaramillo Flórez, María Consuelo | - |
| dc.contributor.author | Mora Arango, Cristina Lucía | - |
| dc.contributor.author | Vélez, Luis Esteban | - |
| dc.contributor.author | Quijano Tobón, Jairo | - |
| dc.date.accessioned | 2024-02-18T15:25:43Z | - |
| dc.date.available | 2024-02-18T15:25:43Z | - |
| dc.date.issued | 2006 | - |
| dc.identifier.issn | 1827-8620 | - |
| dc.identifier.uri | https://hdl.handle.net/10495/38198 | - |
| dc.description.abstract | ABSTRACT: The appearance of bacterial resitance due to β-lactamase enzyme is frequent in Colombia and it has important consequences in term of morbidity and mortality. The inhibitory evaluation of the β-lactamase enzyme of 5 compounds gave as a result more powerful compounds than clavulanic acid. The more active chalcones establish hydrogen bonds with Ser, Tyr and Lys amino acids, the high number of hydrogen bonds between the compound and the amino acid increases the affinity and the inhibitory activity. In accordance with the results, the compounds might inhibit irreversibly the β-lactamase enzyme. | spa |
| dc.format.extent | 6 páginas | spa |
| dc.format.mimetype | application/pdf | spa |
| dc.language.iso | eng | spa |
| dc.publisher | University of Salerno | spa |
| dc.type.hasversion | info:eu-repo/semantics/publishedVersion | spa |
| dc.rights | info:eu-repo/semantics/openAccess | spa |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/2.5/co/ | * |
| dc.title | Biological evaluation of aromatic compounds as B-Lactamase inhibitors | spa |
| dc.type | info:eu-repo/semantics/article | spa |
| dc.publisher.group | Grupo de Investigación en Sustancias Bioactivas (GISB) | spa |
| oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 | spa |
| dc.rights.accessrights | http://purl.org/coar/access_right/c_abf2 | spa |
| oaire.citationtitle | Pharmacologyonline | spa |
| oaire.citationstartpage | 650 | spa |
| oaire.citationendpage | 655 | spa |
| oaire.citationvolume | 3 | spa |
| dc.rights.creativecommons | https://creativecommons.org/licenses/by-nc-nd/4.0/ | spa |
| dc.publisher.place | Salerno, Italia | spa |
| dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | spa |
| dc.type.redcol | https://purl.org/redcol/resource_type/ART | spa |
| dc.type.local | Artículo de investigación | spa |
| dc.subject.decs | beta-Lactamasas | - |
| dc.subject.decs | beta-Lactamases | - |
| dc.subject.decs | Ácido Clavulánico | - |
| dc.subject.decs | Clavulanic Acid | - |
| dc.subject.decs | Inhibidores Enzimáticos | - |
| dc.subject.decs | Enzyme Inhibitors | - |
| dc.subject.decs | Amoxicilina | - |
| dc.subject.decs | Amoxicillin | - |
| dc.subject.decs | Chalcona | - |
| dc.subject.decs | Chalcone | - |
| dc.description.researchgroupid | COL0010359 | spa |
| dc.subject.meshuri | https://id.nlm.nih.gov/mesh/D001618 | - |
| dc.subject.meshuri | https://id.nlm.nih.gov/mesh/D019818 | - |
| dc.subject.meshuri | https://id.nlm.nih.gov/mesh/D004791 | - |
| dc.subject.meshuri | https://id.nlm.nih.gov/mesh/D000658 | - |
| dc.subject.meshuri | https://id.nlm.nih.gov/mesh/D002599 | - |
| dc.relation.ispartofjournalabbrev | Pharmacologyonline | spa |
| Aparece en las colecciones: | Artículos de Revista en Farmacéutica y Alimentarias | |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| JaramilloConsuelo_2006_Biological_Evaluation_Aromatic.pdf | Artículo de investigación | 128.53 kB | Adobe PDF | Visualizar/Abrir |
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