Por favor, use este identificador para citar o enlazar este ítem: https://hdl.handle.net/10495/38742
Registro completo de metadatos
Campo DC Valor Lengua/Idioma
dc.contributor.authorAgudelo Gómez, Lee Solbay-
dc.contributor.authorBetancur Galvis, Liliana Amparo-
dc.contributor.authorGonzález Cardenete, Miguel Ángel-
dc.date.accessioned2024-03-25T23:20:31Z-
dc.date.available2024-03-25T23:20:31Z-
dc.date.issued2012-
dc.identifier.citationAgudelo-Gómez, L. S., Betancur-Galvis, L. A., & González, M. A. (2012). Anti HHV-1 and HHV-2 activity in vitro of abietic and dehydroabietic acid derivatives. Pharmacologyonline, 1(1), 36-42.spa
dc.identifier.issn1827-8620-
dc.identifier.urihttps://hdl.handle.net/10495/38742-
dc.description.abstractABSTRACT: Herpes Simplex Virus types 1 and 2 (HHV-1 and HHV-2) are human neurotropic viruses that infect most commonly the oral and genital area, respectively. Resistant viral isolates can be observed especially in immunocompromised patients. This scenario has triggered the search for new antiherpetic agents, especially those with mechanisms of action different to nucleoside analogs. The antiviral activity in vitro for abietic and dehydroabietic acid and controls [acyclovir (ACV), and heparin (HEP)] was evaluated against HHV-1 and HHV-2 using end-point titration technique (EPTT) with a few modifications. The compounds methyl abietate [2], abietinal [4], 8,13(15)-abietadien-18-oic acid [5], methyl abieta-8,13(15)-dien-18-oate [6], 8,13(15)-abietadien-18- ol [7] and dehydroabietinol acetate [11] showed significant anti-herpetic activity of broad-spectrum.spa
dc.format.extent7 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherUniversity of Salernospa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.rightsinfo:eu-repo/semantics/openAccessspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/*
dc.titleAnti HHV-1 and HHV-2 activity in vitro of abietic and dehydroabietic acid derivativesspa
dc.typeinfo:eu-repo/semantics/articlespa
dc.publisher.groupGRID - Grupo de Investigación Dermatológicaspa
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2spa
oaire.citationtitlePharmacologyonlinespa
oaire.citationstartpage36spa
oaire.citationendpage42spa
oaire.citationvolume1spa
oaire.citationissue1spa
dc.rights.creativecommonshttps://creativecommons.org/licenses/by-nc-nd/4.0/spa
dc.publisher.placeSalerno, Italyspa
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa
dc.type.redcolhttps://purl.org/redcol/resource_type/ARTspa
dc.type.localArtículo de investigaciónspa
dc.subject.decsHerpesvirus Humano 1-
dc.subject.decsHerpesvirus 1, Human-
dc.subject.decsHerpesvirus Humano 2-
dc.subject.decsHerpesvirus 2, Human-
dc.subject.decsAntivirales-
dc.subject.decsAntiviral Agents-
dc.subject.proposalÁcido abiéticospa
dc.subject.proposalAbietic acidspa
dc.subject.proposalÁcido deshidroabiéticospa
dc.subject.proposalDehydroabietic acidspa
dc.description.researchgroupidCOL0050839spa
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D018259-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D018258-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D000998-
dc.relation.ispartofjournalabbrevPharmacologyonlinespa
Aparece en las colecciones: Artículos de Revista en Ciencias Médicas

Ficheros en este ítem:
Fichero Descripción Tamaño Formato  
GomezLee_2012_AntiHHV-1_Dehydroabietic_Acid.pdfArtículo de investigación706.18 kBAdobe PDFVisualizar/Abrir


Este ítem está sujeto a una licencia Creative Commons Licencia Creative Commons Creative Commons