1. Repositorio Institucional Universidad de Antioquia
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  3. Instituto de Investigaciones Médicas
  4. Artículos de Revista en Ciencias Médicas
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dc.contributor.authorLopera Restrepo, Francisco Javier-
dc.contributor.authorLangbaum, Jessica B.-
dc.contributor.authorTariot, Pierre N.-
dc.contributor.authorReiman, Eric M.-
dc.contributor.authorBateman, Randall J.-
dc.contributor.authorMorris, John C.-
dc.contributor.authorSperling, Reisa A.-
dc.contributor.authorAisen, Paul S.-
dc.contributor.authorRoses, Allen D.-
dc.contributor.authorWelsh Bohmer, Kathleen A.-
dc.contributor.authorCarrillo, Maria C.-
dc.contributor.authorWeninger, Stacie-
dc.date.accessioned2024-06-03T12:58:52Z-
dc.date.available2024-06-03T12:58:52Z-
dc.date.issued2016-
dc.identifier.issn1759-4758-
dc.identifier.urihttps://hdl.handle.net/10495/39580-
dc.description.abstractABSTRACT: If we are to find treatments to postpone, reduce the risk of, or completely prevent the clinical onset of Alzheimer disease (AD), we need faster methods to evaluate promising preclinical AD treatments, new ways to work together in support of common goals, and a determination to expedite the initiation and performance of preclinical AD trials. In this article, we note some of the current challenges, opportunities and emerging strategies in preclinical AD treatment. We describe the Collaboration for Alzheimer's Prevention (CAP)-a convening, harmonizing and consensus-building initiative to help stakeholders advance AD prevention research with rigour, care and maximal impact-and we demonstrate the impact of CAP on the goals and design of new preclinical AD trials.spa
dc.format.extent14 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherNature Researchspa
dc.type.hasversioninfo:eu-repo/semantics/acceptedVersionspa
dc.rightsinfo:eu-repo/semantics/openAccessspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/*
dc.titleCAP—advancing the evaluation of preclinical Alzheimer disease treatmentsspa
dc.typeinfo:eu-repo/semantics/articlespa
dc.publisher.groupGrupo de Neurociencias de Antioquiaspa
dc.identifier.doi10.1038/nrneurol.2015.177-
oaire.versionhttp://purl.org/coar/version/c_ab4af688f83e57aaspa
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2spa
dc.identifier.eissn1759-4766-
oaire.citationtitleNature Reviews Neurologyspa
oaire.citationstartpage1spa
oaire.citationendpage14spa
oaire.citationvolume12spa
oaire.citationissue1spa
dc.rights.creativecommonshttps://creativecommons.org/licenses/by-nc-nd/4.0/spa
dc.publisher.placeLondres, Inglaterraspa
dc.type.coarhttp://purl.org/coar/resource_type/c_dcae04bcspa
dc.type.redcolhttps://purl.org/redcol/resource_type/ARTREVspa
dc.type.localArtículo de revisiónspa
dc.subject.decsAnciano de 80 o más Años-
dc.subject.decsAged, 80 and over-
dc.subject.decsEnfermedad de Alzheimer-
dc.subject.decsAlzheimer Disease-
dc.subject.decsFarmacoterapia-
dc.subject.decsDrug Therapy-
dc.subject.decsDiagnóstico-
dc.subject.decsDiagnosis-
dc.subject.decsGenética-
dc.subject.decsGenetics-
dc.subject.decsDisfunción Cognitiva-
dc.subject.decsCognitive Dysfunction-
dc.subject.decsConducta Cooperativa-
dc.subject.decsCooperative Behavior-
dc.subject.decsProgresión de la Enfermedad-
dc.subject.decsDisease Progression-
dc.subject.decsEvaluación Preclínica de Medicamentos-
dc.subject.decsDrug Evaluation, Preclinical-
dc.subject.decsDiagnóstico Precoz-
dc.subject.decsEarly Diagnosis-
dc.subject.decsAdhesión a Directriz-
dc.subject.decsGuideline Adherence-
dc.subject.decsComunicación Interdisciplinaria-
dc.subject.decsInterdisciplinary Communication-
dc.subject.decsPruebas Neuropsicológicas-
dc.subject.decsNeuropsychological Tests-
dc.subject.decsNootrópicos-
dc.subject.decsNootropic Agents-
dc.subject.decsSíntomas Prodrómicos-
dc.subject.decsProdromal Symptoms-
dc.subject.decsEnsayos Clínicos Controlados Aleatorios como Asunto-
dc.subject.decsRandomized Controlled Trials as Topic-
dc.subject.decsResultado del Tratamiento-
dc.subject.decsTreatment Outcome-
dc.description.researchgroupidCOL0010744spa
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D000369-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D000544-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D004358-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D003933-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D005823-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D060825-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D003299-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D018450-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D004353-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D042241-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D019983-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D033183-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D009483-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D018697-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D062706-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D016032-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D016896-
dc.relation.ispartofjournalabbrevNat. Rev. Neurol.spa
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