Por favor, use este identificador para citar o enlazar este ítem:
https://hdl.handle.net/10495/41551Registro completo de metadatos
| Campo DC | Valor | Lengua/Idioma |
|---|---|---|
| dc.contributor.author | Urrea Tavera, Cristian Stalyn | - |
| dc.contributor.author | Mejía de los Ríos, Susana Pamela | - |
| dc.contributor.author | Orozco Holguín, Jahir | - |
| dc.contributor.conferencename | International Student Congress Of (bio)Medical Sciences, ISCOMS 2024 (del 3 al 7 de junio de 2024 : University Medical Center Groningen, Groningen, Países Bajos) | spa |
| dc.date.accessioned | 2024-08-28T14:03:24Z | - |
| dc.date.available | 2024-08-28T14:03:24Z | - |
| dc.date.issued | 2024-06-04 | - |
| dc.identifier.uri | https://hdl.handle.net/10495/41551 | - |
| dc.description.abstract | ABSTRACT: Colorectal cancer (CRC) presents challenges due to the limited effectiveness and side effects of conventional treatments like chemotherapy and surgery. Nanobioconjugates, such as poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs), offer improved drug delivery alternatives. Peptides bonded to CRC receptors show potential as therapies and vaccines. This study encapsulates the P1 peptide in PLGA-PEG-Mal NPs, functionalized with the G3 peptide for targeted CRC cell delivery to inhibit cell proliferation1,2, and encapsulates the P2 peptide in PLGA-COOH polymer to inhibit tumor growth via CD8+ T-cell activation, using D-mannosamine for targeting antigen-presenting cells 3,4. By studying the physicochemical properties of PLGA and peptides, the research aims to enhance stability and controlled release while minimizing side effects and improving CRC therapy from nanobioconjugates and peptide synergies. | spa |
| dc.format.mimetype | application/pdf | spa |
| dc.language.iso | eng | spa |
| dc.type.hasversion | info:eu-repo/semantics/publishedVersion | spa |
| dc.rights | info:eu-repo/semantics/openAccess | spa |
| dc.rights.uri | http://creativecommons.org/licenses/by/2.5/co/ | * |
| dc.title | Nanobioconjugates for targeted delivery of antigenic and therapeutic peptides at colorectal cancer | spa |
| dc.type | info:eu-repo/semantics/conferenceObject | spa |
| dc.publisher.group | Grupo Tandem en Nano-bio-física | spa |
| oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 | spa |
| dc.rights.accessrights | http://purl.org/coar/access_right/c_abf2 | spa |
| oaire.citationtitle | International Student Congress Of (bio)Medical Sciences, ISCOMS 2024 | spa |
| oaire.citationconferenceplace | University Medical Center Groningen, Groningen, Países Bajos | spa |
| oaire.citationconferencedate | 2024-06-03/2024-06-07 | spa |
| dc.rights.creativecommons | https://creativecommons.org/licenses/by/4.0/ | spa |
| oaire.fundername | Colombia. Ministerio de Ciencia, Tecnología e Innovación - MinCiencias | spa |
| dc.type.coar | http://purl.org/coar/resource_type/c_6670 | spa |
| dc.type.redcol | https://purl.org/redcol/resource_type/EC | spa |
| dc.type.local | Póster de conferencia | spa |
| dc.subject.decs | Neoplasias Colorrectales | - |
| dc.subject.decs | Colorectal Neoplasms | - |
| dc.subject.decs | Péptidos | - |
| dc.subject.decs | Peptides | - |
| dc.subject.decs | Antígenos | - |
| dc.subject.decs | Antigens | - |
| dc.subject.decs | Nanopartículas | - |
| dc.subject.decs | Nanoparticles | - |
| dc.subject.decs | Copolímero de Ácido Poliláctico-Ácido Poliglicólico | - |
| dc.subject.decs | Polylactic Acid-Polyglycolic Acid Copolymer | - |
| dc.subject.decs | Receptores CCR | - |
| dc.subject.decs | Receptors, CCR | - |
| dc.subject.proposal | Nanobioconjugado | spa |
| oaire.awardtitle | Desarrollo de nanovehículos funcionales para el transporte y liberación específica de principios terapéuticos contra el cáncer de colon | spa |
| dc.description.researcharea | Biomateriales, Nanotecnología, Medicina de Precisión | spa |
| dc.description.researchgroupid | COL0202529 | spa |
| dc.description.researchcost | $5.624.481.000 | spa |
| oaire.awardnumber | MinCiencias 2023-58290 (convocatoria 920-2022) | spa |
| dc.subject.meshuri | https://id.nlm.nih.gov/mesh/D015179 | - |
| dc.subject.meshuri | https://id.nlm.nih.gov/mesh/D010455 | - |
| dc.subject.meshuri | https://id.nlm.nih.gov/mesh/D000941 | - |
| dc.subject.meshuri | https://id.nlm.nih.gov/mesh/D053758 | - |
| dc.subject.meshuri | https://id.nlm.nih.gov/mesh/D000077182 | - |
| dc.subject.meshuri | https://id.nlm.nih.gov/mesh/D054388 | - |
| oaire.funderidentifier.ror | RoR:03fd5ne08 | - |
| Aparece en las colecciones: | Documentos de conferencias en Ciencias Exactas y Naturales | |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| UrreaCristian_2024_Nanobioconjugates_Targeted_Antigenic.pdf | Póster de conferencia | 925.12 kB | Adobe PDF | Visualizar/Abrir |
| UrreaCristian_2024_Nanobioconjugates_Targeted_Antigenic-Resumen.pdf | Resumen | 145.62 kB | Adobe PDF | Visualizar/Abrir |
Este ítem está sujeto a una licencia Creative Commons Licencia Creative Commons
