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dc.contributor.authorRuiz Hernández, Orville-
dc.contributor.authorCruz Leite, Vanessa-
dc.contributor.authorMilhomem, Rafaela-
dc.contributor.authorMoreira André, Luís Elias-
dc.contributor.authorMattos, Karine-
dc.contributor.authorPaccez, Juliano Domiraci-
dc.contributor.authorMorais, Inácio Moisés-
dc.contributor.authorVenturini, James-
dc.contributor.authorMelhem Marcia, de Souza Carvalho-
dc.contributor.authorPaniago, Anamaria Mello Miranda-
dc.contributor.authorSoares, Célia Maria de Almeida-
dc.contributor.authorWeber Schneider, Simone-
dc.contributor.authorBorges Clayton, Luiz-
dc.date.accessioned2024-09-14T14:41:44Z-
dc.date.available2024-09-14T14:41:44Z-
dc.date.issued2022-
dc.identifier.citationInácio MM, Cruz-Leite VRM, Moreira ALE, Mattos K, Paccez JD, Ruiz OH, Venturini J, de Souza Carvalho Melhem M, Paniago AMM, de Almeida Soares CM, Weber SS, Borges CL. Challenges in Serologic Diagnostics of Neglected Human Systemic Mycoses: An Overview on Characterization of New Targets. Pathogens. 2022 May 11;11(5):569. doi: 10.3390/pathogens11050569.spa
dc.identifier.urihttps://hdl.handle.net/10495/42104-
dc.description.abstractABSTRACT: Systemic mycoses have been viewed as neglected diseases and they are responsible for deaths and disabilities around the world. Rapid, low-cost, simple, highly-specific and sensitive diagnostic tests are critical components of patient care, disease control and active surveillance. However, the diagnosis of fungal infections represents a great challenge because of the decline in the expertise needed for identifying fungi, and a reduced number of instruments and assays specific to fungal identification. Unfortunately, time of diagnosis is one of the most important risk factors for mortality rates from many of the systemic mycoses. In addition, phenotypic and biochemical identification methods are often time-consuming, which has created an increasing demand for new methods of fungal identification. In this review, we discuss the current context of the diagnosis of the main systemic mycoses and propose alternative approaches for the identification of new targets for fungal pathogens, which can help in the development of new diagnostic tests.spa
dc.format.extent34 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherMDPIspa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersionspa
dc.rightsinfo:eu-repo/semantics/openAccessspa
dc.rights.urihttp://creativecommons.org/licenses/by/2.5/co/*
dc.titleChallenges in Serologic Diagnostics of Neglected Human Systemic Mycoses: An Overview on Characterization of New Targetsspa
dc.typeinfo:eu-repo/semantics/articlespa
dc.publisher.groupBiología Celular y Molecular CIB U. de A. U. del Rosariospa
dc.publisher.groupGrupo de Investigación en Microbiología Básica y Aplicada-Microbaspa
dc.identifier.doi10.3390/pathogens11050569-
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2spa
dc.identifier.eissn2076-0817-
oaire.citationtitlePathogensspa
oaire.citationstartpage1spa
oaire.citationendpage34spa
oaire.citationvolume11spa
oaire.citationissue5spa
dc.rights.creativecommonshttps://creativecommons.org/licenses/by/4.0/spa
oaire.fundernameConselho Nacional de Desenvolvimento Científico e Tecnológicospa
oaire.fundernameFundação de Apoio a Pesquisa do Estado de Goiásspa
oaire.fundernameCoordenação de Aperfeicoamento de Pessoal de Nível Superiorspa
dc.publisher.placeBasilea, Suizaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_dcae04bcspa
dc.type.redcolhttps://purl.org/redcol/resource_type/ARTREVspa
dc.type.localArtículo de revisiónspa
dc.subject.decsMicosis-
dc.subject.decsMycoses-
dc.subject.decsDiagnóstico-
dc.subject.decsDiagnosis-
dc.subject.decsSimulación por Computador-
dc.subject.decsComputer Simulation-
dc.subject.decsDesarrollo Experimental-
dc.subject.decsExperimental Development-
dc.description.researchgroupidCOL0000962spa
dc.description.researchgroupidCOL0126131spa
oaire.awardnumberCAPES 88882.458447/2019-01spa
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D009181-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D003933-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D003198-
dc.relation.ispartofjournalabbrevPathogensspa
oaire.funderidentifier.rorRoR:03swz6y49-
oaire.funderidentifier.rorRoR:00w8cq239-
oaire.funderidentifier.rorRoR:00x0ma614-
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