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https://hdl.handle.net/10495/7347| Título : | Statistical properties of the quantile normalization method for density curve alignment |
| Autor : | Gallón Gómez, Santiago Alejandro Loubes, Jean Michel Maza, Elie |
| metadata.dc.subject.*: | Wasserstein distance Curve registration Manifold registration Microarray data analysis Normalization Order statistics Structural expectation |
| Fecha de publicación : | 2013 |
| Editorial : | Elsevier |
| Citación : | Gallón Gómez, S. A., Loubes, J. M. & Maza, E. (2013). Statistical properties of the quantile normalization method for density curve alignment. Mathematical Biosciences, 242(2), 129-142. |
| Resumen : | ABSTRACT: The article investigates the large sample properties of the quantile normalization method by Bolstad et al. (2003) [4] which has become one of the most popular methods to align density curves in microarray data analysis. We prove consistency of this method which is viewed as a particular case of the structural expectation procedure for curve alignment, which corresponds to a notion of barycenter of measures in the Wasserstein space. Moreover, we show that, this method fails in some case of mixtures, and we propose a new methodology to cope with this issue. |
| metadata.dc.identifier.eissn: | 1879-3134 |
| ISSN : | 0025-5564 |
| metadata.dc.identifier.doi: | 10.1016/j.mbs.2012.12.007 |
| Aparece en las colecciones: | Artículos de Revista en Ciencias Económicas |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| GallonSantiago_2013_StatisticalPropertiesQuantile.pdf | Artículo de investigación | 7.1 MB | Adobe PDF | Visualizar/Abrir |
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