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Título : Sistematización de las investigaciones que evalúan la asociación de la infección con parásitos y cáncer
Otros títulos : Systematization of studies that evaluate the link between infections by parasites and cancer
Autor : Calderón, Andrés Mauricio
Panesso Restrepo, Yeison
Galván Díaz, Ana Luz
metadata.dc.subject.*: parásitos
Fecha de publicación : 2017
Editorial : Universidad de Antioquia, Escuela de Microbiología
Citación : Calderón AM, Panesso-Restrepo Y, Galván-Díaz AL, Bedoya AM. Sistematización de las investigaciones que evalúan la asociación de la infección con parásitos y cáncer. Hechos Microbiol. 2017;8(1-2):56-69.
Resumen : Introduction: cancer is one of the main causes of death in the world. It is estimated that between 16 and 20% of cancer cases are produced by infectious agents. The aim of this review was to systematize studies that describe the relationship between parasites and cancer. Methods: a systematic review of original studies was conducted by completing the identification, screening, eligibility and inclusion phases. The reproducibility of the study was guaranteed through the application of the research protocol by two researchers, independently. Results: out of 233,613 publications identified in the electronic databases, a total of 229 articles were included in this study. A total of twenty-seven (27) parasites were found to be associated with thirty-nine (39) types of cancer. Helminths constituted the main group of parasites related to cancer, being Schistosoma haematobium the most commonly studied. The descriptive (n = 86) and experimental (n = 75) studies were the most frequent, while few cohort studies (n = 3) and cases and controls (n = 1) were reported. The mechanism of carcinogenesis was established for 9 parasite species, three (3) of which are classed by the International Agency for Research on Cancer (IARC) as group 1 carcinogens (Clonorchis sinensis, Opisthorchis viverrini and Schistosoma haematobium), and one (1) as 2B subgroup (Schistosoma japonicum), which includes possible carcinogens. Conclusion: the studies showed that parasites not included by the IARC in its classification are described as carcinogenic. The fact that their potential as carcinogens is still overlooked may represent an important cause of cancer.
ISSN : 2145-8898
Aparece en las colecciones: Centro de Investigación y Extensión de la Escuela de Microbiología

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