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Título : Sinu virus, a novel and divergent orthomyxovirus related to members of the genus Thogotovirus isolated from mosquitoes in Colombia
Autor : Contreras Gutiérrez, María Angelica
Nunes, Marcio
Guzman, Hilda
Uribe Soto, Sandra
Gallego Gómez, Juan Carlos
Suaza Vasco, Juan David
Cardoso, Jedson
Popov, Vsevolod
Widen, Steven
Wood, Thomas
Vasilakisd, Nikos
Tesh, Robert
metadata.dc.subject.*: Thogotovirus
Ortomixovirus
Orthomyxoviruses
Sinu virus
Thogotovirus genus
Insect-specific viruses
Fecha de publicación : 2017
Editorial : Academic Press
Resumen : ABSTRACT: The genome and structural organization of a novel insect-specific orthomyxovirus, designated Sinu virus, is described. Sinu virus (SINUV) was isolated in cultures of C6/36 cells from a pool of mosquitoes collected in northwestern Colombia. The virus has six negative-sense ssRNA segments. Genetic analysis of each segment demonstrated the presence of six distinct ORFs encoding the following genes: PB2 (Segment 1), PB1, (Segment 2), PA protein (Segment 3), envelope GP gene (Segment 4), the NP (Segment 5), and M-like gene (Segment 6). Phylogenetically, SINUV appears to be most closed related to viruses in the genus Thogotovirus.
metadata.dc.identifier.eissn: 1096-0341
ISSN : 0042-6822
metadata.dc.identifier.doi: 10.1016/j.virol.2016.11.014
Aparece en las colecciones: Artículos de Revista en Ciencias Médicas

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