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dc.contributor.authorQuintana Castillo, Juan Carlos-
dc.contributor.authorVargas Muñoz, Leidy Johana-
dc.contributor.authorSegura Latorre, Cesar-
dc.contributor.authorEstrada Gómez, Sebastián-
dc.contributor.authorBueno Sánchez, Julio César-
dc.contributor.authorAlarcón Pérez, Juan Carlos-
dc.date.accessioned2021-11-11T16:04:35Z-
dc.date.available2021-11-11T16:04:35Z-
dc.date.issued2018-
dc.identifier.urihttp://hdl.handle.net/10495/23931-
dc.description.abstractABSTRACT: The Colombian rattlesnake Crotalus durissus cumanensis is distributed in three geographic zones of the country: the Atlantic Coast, the upper valley of the Magdalena River, and the eastern plains of the Colombian Orinoquía. Its venom induces neurological symptoms, such as eyelid ptosis, myasthenic facies, and paralysis of the respiratory muscles, which can lead to death. Identification and analysis of C. d. cumanensis showed nine groups of proteins responsible for the neurotoxic effect, of which the crotoxin complex was the most abundant (64.71%). Immunorecognition tests of C. d. cumanensis showed that the use of a commercial antivenom manufactured in Mexico resulted in immunoreactivity.spa
dc.format.extent12spa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherMDPIspa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersionspa
dc.rightsinfo:eu-repo/semantics/openAccessspa
dc.rights.urihttp://creativecommons.org/licenses/by/2.5/co/*
dc.titleCharacterization of the venom of C. d. cumanesis of Colombia : Proteomic analysis and antivenomic studyspa
dc.typeinfo:eu-repo/semantics/articlespa
dc.publisher.groupGrupo Malariaspa
dc.publisher.groupGrupo Reproducciónspa
dc.publisher.groupToxinología Alternativas Terapéuticas y Alimentariasspa
dc.identifier.doi10.3390/toxins10020085-
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2spa
dc.identifier.eissn2072-6651-
oaire.citationtitleToxinsspa
oaire.citationstartpage1spa
oaire.citationendpage12spa
oaire.citationvolume10spa
oaire.citationissue2spa
dc.rights.creativecommonshttps://creativecommons.org/licenses/by/4.0/spa
dc.publisher.placeBasilea, Suizaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa
dc.type.redcolhttps://purl.org/redcol/resource_type/ARTspa
dc.type.localArtículo de investigaciónspa
dc.subject.decsVenenos de Serpiente-
dc.subject.decsSnake Venoms-
dc.subject.decsPéptidos-
dc.subject.decsPeptides-
dc.subject.proposalC. d. cumanensis venomspa
dc.subject.proposalHPLC-nESI-MS/MSspa
dc.description.researchgroupidCOL0007631spa
dc.description.researchgroupidCOL0007524spa
dc.description.researchgroupidCOL0014476spa
dc.relation.ispartofjournalabbrevToxinsspa
Aparece en las colecciones: Artículos de Revista en Farmacéutica y Alimentarias

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