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https://hdl.handle.net/10495/36494| Título : | Antiprotozoal Activity of Ethanol Extracts of Some Bomarea Species |
| Autor : | Alzate Guarín, Fernando Jiménez Úsuga, Nora Del Socorro Weniger, Bernard Bastida Armengol, Jaume Gimenez, Alberto Ruiz, Grace |
| metadata.dc.subject.*: | Liliales Biodiversidad Biodiversity Fitoalexinas Phytoalexins Enfermedades Transmisibles Communicable Diseases Terapéutica Therapeutics Colombia Bomarea |
| Fecha de publicación : | 2008 |
| Editorial : | Taylor and Francis Open Access |
| Citación : | Fernando Alzate, Nora Jimenez, Bernard Weniger, Jaume Bastida & Alberto Gimenez (2008) Antiprotozoal Activity of Ethanol Extracts of Some Bomarea Species, Pharmaceutical Biology, 46:9, 575-578, DOI: 10.1080/13880200801968904 |
| Resumen : | ABSTRACT: The antiprotozoal activity of 26 ethanol extracts derived from 13 species of the genus Bomarea (Alstroemeriaceae) were evaluated against the promastigote forms of three Leishmania species (L. amazonensis L.,L. braziliensis Vianna, and L. donovani Laveran & Mesnil) and the epimastigote form of Trypanosoma cruzi Chagas. IC50 values for leishmanicidal activities were between 4.9 and 98.6 μg/mL, B. setacea extracts being the most active against the three species of Leishmania. Amphotericin B (IC50 = 0.2 μg/mL) and pentamidine (IC50 = 10 μg/mL) were used as control in this assay. IC50 values for antitrypanosomal activities were between 65.2 and 92.7 μg/mL, whereas the control benznidazole had an IC50 value of 2 μg/mL. |
| metadata.dc.identifier.eissn: | 1744-5116 |
| ISSN : | 1388-0209 |
| metadata.dc.identifier.doi: | 10.1080/13880200801968904 |
| Aparece en las colecciones: | Artículos de Revista en Farmacéutica y Alimentarias |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| AlzateFernando_2008_Antiprotozoal_Activity.pdf | Artículo de investigación | 246.05 kB | Adobe PDF | Visualizar/Abrir |
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