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https://hdl.handle.net/10495/37177
Título : | Study of SARS-CoV-2 spike protein interaction with macrophages in presence of vitamin D |
Autor : | di Filippo Villa, Diana Carolina Montoya Guzmán, Melissa López Osorio, María Camila Urcuqui Inchima, Silvio Jaimes, Javier A. Navas Navas, María Cristina |
metadata.dc.subject.*: | SARS-CoV-2 Macrófagos Macrophages Deficiencia de Vitamina D Vitamin D Deficiency |
metadata.dc.contributor.conferencename: | Annual meeting of American Society for Virology (41 : Del 16 al 20 de julio de 2022, University of Wisconsin, Madison, Estados Unidos) |
Fecha de publicación : | 2022 |
Resumen : | ABSTRACT: The macrophages are one of the most important cell populations playing a role in the development of the inflammatory response in SARS-CoV-2 infection. Indeed, the altered function of macrophages in cases of severe COVID-19 leads to a hyperactivated inflammatory response possibly due to damage of the respiratory tract epithelium and/or the interaction with viral particles through the recognition of the Toll-like receptors (TLR), even in the absence of active viral replication. Moreover, the activation and function modification of macrophages could be exacerbated in conditions of vitamin D deficiency, as described dengue virus infection. |
Aparece en las colecciones: | Documentos de conferencias en Ciencias Médicas |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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DiFilippoDiana_2022_Study_SARS-CoV-2.pdf | Póster de conferencia | 1.69 MB | Adobe PDF | Visualizar/Abrir |
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