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https://hdl.handle.net/10495/37256| Título : | Antiprotozoal 6-substituted-5,6-dihydro-alpha-pyrones from Raimondia cf. monoica. |
| Autor : | Carmona Pedraza, Doris Sáez Vega, Jairo Antonio Granados Niño, Hillmer Pérez Hernández, Edwin Gregorio Blair Trujillo, Silvia Angulo Soto, Alberto Figadere, Bruno |
| metadata.dc.subject.*: | Annonaceae Antiprotozoarios Antiprotozoal Agents Lactonas Lactones Leishmania Estructura Molecular Molecular Structure Hojas de la Planta Plant Leaves Raíces de Plantas Plant Roots Plasmodium falciparum Pironas Pyrones Malaria |
| Fecha de publicación : | 2003 |
| Editorial : | Taylor and Francis |
| Citación : | Carmona D, Sáez J, Granados H, Pérez E, Blair S, Angulo A, Figadere B. Antiprotozoal 6-substituted-5,6-dihydro-alpha-pyrones from Raimondia cf. monoica. Nat Prod Res. 2003 Aug;17(4):275-80. doi: 10.1080/1057563031000065062. |
| Resumen : | ABSTRACT: Dichloromethane extracts of both the roots and the leaves of Raimondia cf. monoica showed in vitro antiplasmodial and leishmanicidal activities against Plasmodium falciparum and Leishmania panamensis, respectively. Three 6-substituted 5,6-dihydro-2H-pyran-2-ones were isolated. (1) and (2) were identified as (6S)-(5′-oxohepten-1′E,3′E-dienyl)-5,6-dihydro-2H-pyran-2-one (1) and (6R)-(5′-oxohepten-1′Z,3′E-dienyl)-5,6-dihydro-2H-pyran-2-one (2), respectively. (-)-Argentilactone (3) was also isolated. The structure of the new compound (1) was determined by spectroscopic methods; additional spectroscopic data for (2) are reported for the first time |
| metadata.dc.identifier.eissn: | 1478-6427 |
| ISSN : | 1478-6419 |
| metadata.dc.identifier.doi: | 10.1080/1057563031000065062 |
| Aparece en las colecciones: | Artículos de Revista en Ciencias Médicas |
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| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| CarmonaDoris_2010_AntiprotozoalRaimondiaCFMonoica.pdf | Artículo de investigación | 295.19 kB | Adobe PDF | Visualizar/Abrir |
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