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https://hdl.handle.net/10495/38781| Título : | High resistance against clindamycin, metronidazole and amoxicillin in Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans isolates of periodontal disease |
| Autor : | Ardila Medina, Carlos Martín López Hernández, Mayra Alejandra Guzmán Zuluaga, Isabel Cristina |
| metadata.dc.subject.*: | Aggregatibacter actinomycetemcomitans Aggregatibacter actinomycetemcomitans Amoxicilina Amoxicillin Resistencia a Medicamentos Drug Resistance Antiinfecciosos Anti-Infective Agents Clindamicina Clindamycin Farmacorresistencia Bacteriana Drug Resistance, Bacterial Metronidazol Metronidazole Enfermedades Periodontales Periodontal Diseases Porphyromonas gingivalis Antibióticos Antibiotics https://id.nlm.nih.gov/mesh/D016976 https://id.nlm.nih.gov/mesh/D000658 https://id.nlm.nih.gov/mesh/D004351 https://id.nlm.nih.gov/mesh/D000890 https://id.nlm.nih.gov/mesh/D002981 https://id.nlm.nih.gov/mesh/D024881 https://id.nlm.nih.gov/mesh/D008795 https://id.nlm.nih.gov/mesh/D010510 https://id.nlm.nih.gov/mesh/D016966 |
| Fecha de publicación : | 2010 |
| Editorial : | Medicina Oral S.L. |
| Citación : | Ardila CM, López MA, Guzmán IC. High resistance against clindamycin, metronidazole and amoxicillin in Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans isolates of periodontal disease. Med Oral Patol Oral Cir Bucal. 2010 Nov 1;15(6):e947-51. |
| Resumen : | ABSTRACT: Objectives: To test the antimicrobial sensitivity of two periodontal pathogens to a panel of five orally administrable antibiotics in periodontal disease. Study design: A total of 69 isolates of Aggregatibacter actinomycetemcomitans and Porphyromonas gingivalis were processed using culture and biochemical tests. Selected colonies of A. actinomycetemcomitans and P. gingivalis were used to evaluate the antibacterial activity of clindamycin, metronidazole, amoxicillin, moxifloxacin and amoxicillin/clavulanic acid. Results: Susceptibility testing revealed a sensitivity of 100% of A. actinomycetemcomitans and P. gingivalis to moxifloxacin and amoxicillin/clavulanic acid but moderate susceptibilities were found for the rest of antibiotics agents evaluated. Conclusions: The widespread use of antibiotics is reflected in the level of resistance of A. actinomycetemcomitans and P. gingivalis in patients with periodontal infections. This suggests that antibiotic susceptibility testing is necessary to determine efficacy of antimicrobial agents. Clinical studies with antibiotics should take these differences into account. |
| metadata.dc.identifier.eissn: | 1698-6946 |
| ISSN : | 1698-4447 |
| metadata.dc.identifier.doi: | 10.4317/medoral.15.e947 |
| Aparece en las colecciones: | Artículos de Revista en Odontología |
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| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| ArdilaCarlos_2010_High_Resistance_Against.pdf | Artículo de investigación | 349.57 kB | Adobe PDF | Visualizar/Abrir |
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