Por favor, use este identificador para citar o enlazar este ítem: https://hdl.handle.net/10495/41097
Título : Frequency of Aspirin Resistance in Ischemic Stroke Patients and Healthy Controls from Colombia
Autor : Bedoya Berrío, Gabriel de Jesús
Román González, Alejandro
Naranjo González, Carlos Andrés
Cardona Maya, Walter Darío
Vallejo, Dionis
García, Francisco
Franco, Cesar
Álvarez Pelaéz, María Leonor
Tobón Acosta, Luis Ignacio
López, Marta Ibeth
Rúa Molina, Diana Carolina
Cadavid Jaramillo, Ángela Patricia
Torres Hernández, José Domingo
metadata.dc.subject.*: Aspirina
Aspirin
Accidente Cerebrovascular Isquémico
Ischemic Stroke
Colombia
Resistencia a Medicamentos
Drug Resistance
Agregación Plaquetaria
Platelet Aggregation
https://id.nlm.nih.gov/mesh/D001241
https://id.nlm.nih.gov/mesh/D000083242
https://id.nlm.nih.gov/mesh/D003105
https://id.nlm.nih.gov/mesh/D004351
https://id.nlm.nih.gov/mesh/D010974
Fecha de publicación : 2021
Editorial : Hindawi
Wiley Open Access
Citación : Roman-Gonzalez A, Naranjo CA, Cardona-Maya WD, Vallejo D, Garcia F, Franco C, Alvarez L, Tobón LI, López MI, Rua C, Bedoya G, Cadavid Á, Torres JD. Frequency of Aspirin Resistance in Ischemic Stroke Patients and Healthy Controls from Colombia. Stroke Res Treat. 2021 May 21;2021:9924710. doi: 10.1155/2021/9924710.
Resumen : ABSTRACT: Objective: To evaluate the aspirin resistance prevalence in patients with previous ischemic cerebrovascular disease undergoing aspirin therapy for secondary prevention. Materials and methods: Three hundred fifty patients presenting ischemic strokes and 100 healthy controls under aspirin treatment were evaluated using the optic platelet aggregation test. Results: Aspirin resistance was found in 7.4% of the patients with ischemic stroke and 4% of controls. Aspirin resistance was associated with stroke recurrence in univariate analysis (p = 0.004). Aspirin resistance was not associated with smoking, diabetes, or hypercholesterolemia. Conclusion: Aspirin resistance is present in Colombian patients with ischemic stroke as well as in healthy controls.
metadata.dc.identifier.eissn: 2042-0056
ISSN : 2090-8105
metadata.dc.identifier.doi: 10.1155/2021/9924710
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