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https://hdl.handle.net/10495/42869| Título : | Escherichia coli ST471 Producing VIM-4 Metallo-β-Lactamase in Colombia |
| Autor : | Rada Bravo, Ana Mercedes Correa, Adriana Restrepo Pineda, Eliana Capataz Tafur, Cesar Antonio |
| metadata.dc.subject.*: | Antibacterianos Anti-Bacterial Agents Farmacorresistencia Bacteriana Múltiple Drug Resistance, Multiple, Bacterial Genes Bacterianos Genes, Bacterial Pruebas de Sensibilidad Microbiana Microbial Sensitivity Tests beta-Lactamasas beta-Lactamases Escherichia coli https://id.nlm.nih.gov/mesh/D000900 https://id.nlm.nih.gov/mesh/D024901 https://id.nlm.nih.gov/mesh/D005798 https://id.nlm.nih.gov/mesh/D008826 https://id.nlm.nih.gov/mesh/D001618 https://id.nlm.nih.gov/mesh/D004926 |
| Fecha de publicación : | 2022 |
| Editorial : | Mary Ann Liebert |
| Citación : | Rada AM, Correa A, Restrepo E, Capataz C. Escherichia coli ST471 Producing VIM-4 Metallo-β-Lactamase in Colombia. Microb Drug Resist. 2022 Mar;28(3):288-292. doi: 10.1089/mdr.2021.0031. |
| Resumen : | ABSTRACT: An Escherichia coli isolate sequence-type 471 (ST471) producing Verona integron-encoded metallo-blactamases (VIM)-4 was recovered from a rectal swab in a patient without travel records with osteomyelitis in Colombia. The isolate carried a class 1 integron-borne blaVIM-4 gene with a 170-bp duplication in the 3' end of the gene, preceded by an aac(6¢)-Ib gene. The genetic environment of blaVIM-4, blaCMY-2, and sul2 genes showed similarities to the backbone of pKKp4, an IncA/C-type plasmid from a Klebsiella neumoniae strain carrying blaVIM-4 recovered in Kuwait. This is the first report of blaVIM-4 in Enterobacterales in South America. Our results suggest that blaVIM-4 gene was found on an IncA/C-type plasmid that could play a role in the spread of VIM-4 carbapenemase in Colombia. |
| metadata.dc.identifier.eissn: | 1931-8448 |
| ISSN : | 1076-6294 |
| metadata.dc.identifier.doi: | 10.1089/mdr.2021.0031 |
| Aparece en las colecciones: | Artículos de Revista en Ciencias Médicas |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| RadaAna_2022_Escherichia_coli_ST471.pdf | Artículo de investigación | 3.53 MB | Adobe PDF | Visualizar/Abrir |
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