1. Repositorio Institucional Universidad de Antioquia
  2. Investigaciones
  3. Instituto de Investigaciones Médicas
  4. Artículos de Revista en Ciencias Médicas
Por favor, use este identificador para citar o enlazar este ítem: https://hdl.handle.net/10495/43125
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dc.contributor.authorFranco Restrepo, José Luis-
dc.contributor.authorYeganeh, Mehdi-
dc.contributor.authorHenneke, Philipp-
dc.contributor.authorRezaei, Nima-
dc.contributor.authorEhl, Stephan-
dc.contributor.authorThiel, Doerte-
dc.contributor.authorMatamoros, Nuria-
dc.contributor.authorPietrogrande, Cristina-
dc.contributor.authorEspanol, Teresa-
dc.contributor.authorLitzman, Jiri-
dc.contributor.authorSanal, Ozden-
dc.contributor.authorKilic, Sara S.-
dc.contributor.authorBreborowicz, Anna-
dc.contributor.authorPlebani, Alessandro-
dc.contributor.authorRenner, Ellen-
dc.contributor.authorRothenfusser, Simon-
dc.contributor.authorHawn, Thomas R.-
dc.contributor.authorWoellner, Cristina-
dc.contributor.authorGrimbacher, Bodo-
dc.date.accessioned2024-11-04T00:56:19Z-
dc.date.available2024-11-04T00:56:19Z-
dc.date.issued2008-
dc.identifier.citationYeganeh M, Henneke P, Rezaei N, Ehl S, Thiel D, Matamoros N, Pietrogrande C, Espanol T, Litzman J, Franco JL, Sanal O, Kilic SS, Breborowicz A, Plebani A, Renner E, Rothenfusser S, Hawn TR, Woellner C, Grimbacher B. Toll-like receptor stimulation induces higher TNF-alpha secretion in peripheral blood mononuclear cells from patients with hyper IgE syndrome. Int Arch Allergy Immunol. 2008;146(3):190-4. doi: 10.1159/000115886. Epub 2008 Feb 11. PMID: 18268386.spa
dc.identifier.issn1018-2438-
dc.identifier.urihttps://hdl.handle.net/10495/43125-
dc.description.abstractABSTRACT: Hyper IgE syndromes (HIES) are primary immunodeficiency disorders of unknown pathogenesis. Patients are typically affected with 'cold' abscesses of the skin, recurrent cyst-forming pneumonia, chronic mucocutaneous candidiasis and other less frequent features such as progressive skeletal abnormalities. Defective signaling in the Toll-like receptor (TLR) pathways has been suggested as a responsible pathologic mechanism, however, in previous reports, 10 patients revealed no defect in inflammatory cytokine responses to different TLR ligands. Here, we report the increase in pro-inflammatory cytokines TNF-alpha and IL-8, following TLR2 and TLR4 stimulation in a larger cohort of 25 additional patients with HIES, and provide a meta-analysis of the TLR data in HIES.spa
dc.format.extent5 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherKarger Publishersspa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersionspa
dc.rightsinfo:eu-repo/semantics/openAccessspa
dc.rights.uriAn error occurred getting the license - uri.*
dc.titleToll-like receptor stimulation induces higher TNF-alpha secretion in peripheral blood mononuclear cells from patients with hyper IgE syndromespa
dc.typeinfo:eu-repo/semantics/articlespa
dc.publisher.groupInmunodeficiencias Primariasspa
dc.identifier.doi10.1159/000115886-
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2spa
dc.identifier.eissn1423-0097-
oaire.citationtitleInternational Archives of Allergy and Immunologyspa
oaire.citationstartpage190spa
oaire.citationendpage194spa
oaire.citationvolume146spa
oaire.citationissue3spa
dc.rights.creativecommonshttps://creativecommons.org/licenses/by-nc/4.0/spa
dc.publisher.placeBasilea, Suizaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa
dc.type.redcolhttps://purl.org/redcol/resource_type/ARTspa
dc.type.localArtículo de investigaciónspa
dc.subject.decsCohort Studies-
dc.subject.decsEstudios de Cohortes-
dc.subject.decsInterleukin-8-
dc.subject.decsInterleucina-8-
dc.subject.decsJob Syndrome-
dc.subject.decsSíndrome de Job-
dc.subject.decsLeukocytes, Mononuclear-
dc.subject.decsLeucocitos Mononucleares-
dc.subject.decsLipopolysaccharides-
dc.subject.decsLipopolisacáridos-
dc.subject.decsSignal Transduction-
dc.subject.decsTransducción de Señal-
dc.subject.decsStatistics, Nonparametric-
dc.subject.decsEstadísticas no Paramétricas-
dc.subject.decsToll-Like Receptor 2-
dc.subject.decsToll-Like Receptor 4-
dc.subject.decsReceptor Toll-Like 4-
dc.subject.decsReceptor Toll-Like 2-
dc.subject.decsTumor Necrosis Factor-alpha-
dc.subject.decsFactor de Necrosis Tumoral alfa-
dc.description.researchgroupidCOL0012426spa
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D015331-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D016209-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D007589-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D007963-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D008070-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D015398-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D018709-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D051195-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D051197-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D014409-
dc.relation.ispartofjournalabbrevInt. Arch. Allergy Immunol.spa
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