1. Repositorio Institucional Universidad de Antioquia
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  3. Instituto de Investigaciones Médicas
  4. Artículos de Revista en Ciencias Médicas
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dc.contributor.authorMiranda Brand, Yaneth-
dc.contributor.authorBedoya, Astrid Milena-
dc.contributor.authorBetancur Galvis, Liliana Amparo-
dc.contributor.authorGallego Gómez, Juan Carlos-
dc.date.accessioned2024-11-10T21:00:02Z-
dc.date.available2024-11-10T21:00:02Z-
dc.date.issued2022-
dc.identifier.citationMiranda Brand Y, Bedoya AM, Betancur-Galvis L, Gallego-Gómez JC. The Colombian Zika Virus Isolate (COL345Si) Replicates in Prostate Adenocarcinoma Cells and Modulates the Antiviral Response. Microorganisms. 2022 Dec 7;10(12):2420. doi: 10.3390/microorganisms10122420.spa
dc.identifier.urihttps://hdl.handle.net/10495/43348-
dc.description.abstractABSTRACT: Zika virus (ZIKV), a flavivirus that is mainly transmitted by A. aegypti and A. albopictus and sexual transmission, has been documented and described. The ZIKV RNA detection in the semen of vasectomized men indicates that accessory glands such as the prostate could be a site of virus replication. In this study, we characterized the ZIKV infection, evaluated the antiviral profile, and demonstrated the AXL and TIM-1 expression on the PC3 prostate cell line. It was also determined that PC3 cells are susceptible and permissive to ZIKV infection without altering the cell viability or causing a cytopathic effect. The antiviral profile suggests that the PC3 cells modulate the antiviral response through the suppressor molecule expression, SOCS-1, during a ZIKV infectionspa
dc.format.extent12 páginasspa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherMDPIspa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersionspa
dc.rightsinfo:eu-repo/semantics/openAccessspa
dc.rights.urihttp://creativecommons.org/licenses/by/2.5/co/*
dc.titleThe Colombian Zika Virus Isolate (COL345Si) Replicates in Prostate Adenocarcinoma Cells and Modulates the Antiviral Responsespa
dc.typeinfo:eu-repo/semantics/articlespa
dc.publisher.groupGRID - Grupo de Investigación Dermatológicaspa
dc.publisher.groupGrupo Medicina Molecular y de Translaciónspa
dc.publisher.groupMicrobiología Ambientalspa
dc.identifier.doi10.3390/microorganisms10122420-
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2spa
dc.identifier.eissn2076-2607-
oaire.citationtitleMicroorganismsspa
oaire.citationstartpage1spa
oaire.citationendpage12spa
oaire.citationvolume10spa
oaire.citationissue12spa
dc.rights.creativecommonshttps://creativecommons.org/licenses/by/4.0/spa
oaire.fundernameColombia. Ministerio de Ciencia, Tecnología e Innovación - MinCienciasspa
oaire.fundernameICETEX (Instituto Colombiano de Crédito Educativo y Estudios Técnicos en el Exterior)spa
dc.publisher.placeBasilea, Suizaspa
dc.type.coarhttp://purl.org/coar/resource_type/c_2df8fbb1spa
dc.type.redcolhttps://purl.org/redcol/resource_type/ARTspa
dc.type.localArtículo de investigaciónspa
dc.subject.decsVirus Zika-
dc.subject.decsZika Virus-
dc.subject.decsFlavivirus-
dc.subject.decsAntivirales-
dc.subject.decsAntiviral Agents-
dc.subject.decsPróstata-
dc.subject.decsProstate-
dc.subject.decsInfección por el Virus Zika-
dc.subject.decsZika Virus Infection-
oaire.funderidentifier.localQ3146540-
dc.description.researchgroupidCOL0050839spa
dc.description.researchgroupidCOL0140139spa
dc.description.researchgroupidCOL0040189spa
oaire.awardnumberRC-FP44842-212-2018spa
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D000071244-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D005416-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D000998-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D011467-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D000071243-
dc.relation.ispartofjournalabbrevMicroorganismsspa
oaire.funderidentifier.rorRoR:03fd5ne08-
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