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https://hdl.handle.net/10495/43985| Título : | New insights into a complex fungal pathogen: the case of Paracoccidioides spp |
| Autor : | Hernández Ruíz, Orville González Marín, Ángel Augusto |
| metadata.dc.subject.*: | Aminoácidos Amino Acids Metabolismo de los Hidratos de Carbono Carbohydrate Metabolism Citocinas Cytokines Genoma Fúngico Genome, Fungal Metabolismo de los Lípidos Lipid Metabolism Redes y Vías Metabólicas Metabolic Networks and Pathways Nucleótidos Nucleotides Paracoccidioides Fagocitosis Phagocytosis Filogenia Phylogeny Factores de Virulencia Virulence Factors https://id.nlm.nih.gov/mesh/D000596 https://id.nlm.nih.gov/mesh/D050260 https://id.nlm.nih.gov/mesh/D016207 https://id.nlm.nih.gov/mesh/D016681 https://id.nlm.nih.gov/mesh/D050356 https://id.nlm.nih.gov/mesh/D053858 https://id.nlm.nih.gov/mesh/D009711 https://id.nlm.nih.gov/mesh/D010228 https://id.nlm.nih.gov/mesh/D010587 https://id.nlm.nih.gov/mesh/D010802 https://id.nlm.nih.gov/mesh/D037521 |
| Fecha de publicación : | 2016 |
| Editorial : | Wiley |
| Citación : | Gonzalez A, Hernandez O. New insights into a complex fungal pathogen: the case of Paracoccidioides spp. Yeast. 2016 Apr;33(4):113-28. doi: 10.1002/yea.3147. |
| Resumen : | ABSTRACT: Paracoccidioidomycosis is a systemic mycosis endemic to Latin America, with Paracoccidioides brasiliensis and P. lutzii being the causal agents of this disorder. Several issues have been raised in the 100 years since its discovery and in this article we discuss features of this fascinating fungal pathogen, including its biology, eco-epidemiology and aspects of its pathogenicity. We also consider some of its virulence determinants, the most recent advances in the study of its metabolic pathways and the molecular and genetic research tools developed for this research. We also review the animal models used to study host-fungal interactions and how the host defence mechanisms against this pathogen work. |
| metadata.dc.identifier.eissn: | 1097-0061 |
| ISSN : | 0749-503X |
| metadata.dc.identifier.doi: | 10.1002/yea.3147 |
| Aparece en las colecciones: | Artículos de Revista en Ciencias Médicas |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| GonzalezAngel_2016_ Paracoccidioides_Virulence factors_Metabolic pathways.pdf | Artículo de investigación | 461.49 kB | Adobe PDF | Visualizar/Abrir |
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