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Título : Admixture in Latin America : geographic structure, phenotypic diversity and self-perception of ancestry based on 7,342 individuals
Autor : Ruiz Linares, Andrés
Adhikari, Kaustubh
Acuña Alonzo, Víctor
Quinto Sánchez, Mirsha
Jaramillo, Claudia
Arias Pérez, William Hernán
Fuentes, Macarena
Pizarro, María
Everardo, Paola
De Avila, Francisco
Gómez Valdés, Jorge
León Mimila, Paola
Hunemeier, Tábita
Ramallo, Virginia
Silva de Cerqueira, Caio C.
Burley, Mari Wyn
Konca, Esra
Zagonel de Oliveira, Marcelo
Veronez, Mauricio Roberto
Rubio Codina, Marta
Attanasio, Orazio
Gibbon, Sahra
Ray, Nicolas
Gallo, Carla
Poletti, Giovanni
Rosique Gracia, Javier
Schuler Faccini, Lavinia
Salzano, Francisco M.
Bortolini, Maria Cátira
Cañizales Quintero, Samuel
Rothhammer, Francisco
Bedoya Berrío, Gabriel de Jesús
Balding, David
Gonzalez José, Rolando
Palabras clave : América Latina
América Latina - Geografía
Diversidad
Diversidad genética humana
Fenotipo
Fecha de publicación : 2014
Editorial : Gene Tolls
Citación : Ruiz Linares, A., Adhikari, K., Acuña Alonzo, V., Quinto Sánchez, M., Jaramillo, C., Arias, W., … Gonzalez José, R. (2014). Admixture in Latin America: geographic structure, phenotypic diversity and self-perception of ancestry based on 7.342 individuals. PLoS Genet, 10(9), 1–13. DOI: http://doi.org/https://doi.org/10.1371/journal.pgen.1004572
Resumen: The current genetic makeup of Latin America has been shaped by a history of extensive admixture between Africans, Europeans and Native Americans, a process taking place within the context of extensive geographic and social stratification. We estimated individual ancestry proportions in a sample of 7,342 subjects ascertained in five countries (Brazil, Chile, Colombia, Me´xico and Peru´ ). These individuals were also characterized for a range of physical appearance traits and for selfperception of ancestry. The geographic distribution of admixture proportions in this sample reveals extensive population structure, illustrating the continuing impact of demographic history on the genetic diversity of Latin America. Significant ancestry effects were detected for most phenotypes studied. However, ancestry generally explains only a modest proportion of total phenotypic variation. Genetically estimated and self-perceived ancestry correlate significantly, but certain physical attributes have a strong impact on self-perception and bias self-perception of ancestry relative to genetically estimated ancestry.
Grupo de INV. : Grupo de Investigación Medio Ambiente y Sociedad (MASO)
URI : http://hdl.handle.net/10495/8625
ISSN : 15537404
15537390 E
Aparece en las colecciones: CISH (Centro de Investigaciones Sociales y Humanas)

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