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dc.contributor.authorCarrizosa Moog, Jaime-
dc.contributor.authorDevilat, Marcelo-
dc.date.accessioned2025-02-03T14:51:44Z-
dc.date.available2025-02-03T14:51:44Z-
dc.date.issued1997-
dc.identifier.issn0013-9580-
dc.identifier.urihttps://hdl.handle.net/10495/44632-
dc.description.abstractABSTRACT: Epilepsy tre&d adequately bur with persistenr seizures is termed refractory epilepsy. Schmidt’s scale differentiates refractory epilepsy from inadequately treated epilepsy. We report the clinical characteristics of patients with refractory epilepsy, as well as the seizure evolution according to Schmidt’s pharmacologic scale. Between February and November 1996, we made a prospective follow-up of 15 patients with four or more seizures a month who were receiving antiepileptic drug (AED) treatment. The patients had the following clinical characteristics associated with refractory epilepsy: early age at onset and long duration of the epileptic illness, absence of idiopathic etiology, epileptic syndromes difficult to treat medically, mental handicap, and polytherapy. At first evaluation, Schmidt’s scale identified 60% (9 patients) as undertreated; at the last evaluation, 20% (3 patients) remained in that category. In a mean of 6.6 months, with changes effected in AED regimen, seizure frequency was reduced in 77.9%. In epileptic referral centers, a pharmacologic evaluation scale is recommended to optimize AED treatment in patients considered refractory to therapy. Schmidt’s scale differentiates inadequately treated patients and selects patient with refractory epilepsy as candidates for new AED trials or epileptic surgery.spa
dc.format.extent1 páginaspa
dc.format.mimetypeapplication/pdfspa
dc.language.isoengspa
dc.publisherWiley ; Raven Pressspa
dc.type.hasversioninfo:eu-repo/semantics/publishedVersionspa
dc.rightsinfo:eu-repo/semantics/openAccessspa
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/2.5/co/*
dc.titleRefractary Medical Epilepsy: Treatment and Follow-up with Schmidt’s Scalespa
dc.title.alternativeEpilepsia refractaria médica: manejo y seguimiento de 15 pacientes con la escala de Schmidtspa
dc.typeinfo:eu-repo/semantics/articlespa
dc.publisher.groupGrupo de Investigación Clínica en Enfermedades del Niño y del Adolescente - Pediacienciasspa
oaire.versionhttp://purl.org/coar/version/c_970fb48d4fbd8a85spa
dc.rights.accessrightshttp://purl.org/coar/access_right/c_abf2spa
dc.identifier.eissn1528-1167-
oaire.citationtitleEpilepsiaspa
oaire.citationstartpage9spa
oaire.citationendpage9spa
oaire.citationvolume38spa
oaire.citationissueSuplemento 9spa
dc.rights.creativecommonshttps://creativecommons.org/licenses/by-nc-nd/4.0/spa
dc.publisher.placeNueva York, Estados Unidosspa
dc.type.coarhttp://purl.org/coar/resource_type/c_6501spa
dc.type.redcolhttps://purl.org/redcol/resource_type/ARTDIVspa
dc.type.localArtículo de revistaspa
dc.subject.decsEpilepsia Refractaria-
dc.subject.decsDrug Resistant Epilepsy-
dc.subject.decsEstado Epiléptico-
dc.subject.decsStatus Epilepticus-
dc.description.researchgroupidCOL0058784spa
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D000069279-
dc.subject.meshurihttps://id.nlm.nih.gov/mesh/D013226-
dc.relation.ispartofjournalabbrevEpilepsiaspa
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