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Campo DC | Valor | Lengua/Idioma |
---|---|---|
dc.contributor.author | Betancur Galvis, Liliana Amparo | - |
dc.contributor.author | Checa, Javier | - |
dc.contributor.author | Marco Ventura, Juan Alberto | - |
dc.contributor.author | Estornell, Ernesto | - |
dc.date.accessioned | 2017-10-10T16:53:50Z | - |
dc.date.available | 2017-10-10T16:53:50Z | - |
dc.date.issued | 2003 | - |
dc.identifier.citation | Betancur Galvis, L. A., Checa, J., Marco Ventura, J. A., & Estornell, E. Jatrophane diterpenes from the latex of euphorbia obtusifolia with inhibitory activity on the mammalian mitochondrial respiratory chain. Planta Médica. 2003; 69: 177-178. | spa |
dc.identifier.issn | 0032-0943 | - |
dc.identifier.uri | http://hdl.handle.net/10495/8522 | - |
dc.description.abstract | ABSTARCT: Seven diterpenes isolated of the latex of the Euphorbia obtusifolia were evaluated as inhibitors of the NADH oxidase activity in submitochondrial particles from bovine heart. Compound 2,2,3,5,7,8,9,15-heptahydroxyjatropha-6(17),11-diene-14-one 8,9-diacetate 7-isobutyrate 2.3-bis(2-methylbutyrate), was the most potent inhibitor with an inhibitory concentration (IC50) value of 5.1 ± 0.2 µM. In the present study, some structure-activity trends are suggested for the inhibitory activity of these natural products on the mammalian mitochondrial respiratory chain. | spa |
dc.format.extent | 2 páginas | spa |
dc.format.mimetype | application/pdf | spa |
dc.language.iso | eng | spa |
dc.publisher | Thieme Gruppe | spa |
dc.type.hasversion | info:eu-repo/semantics/publishedVersion | spa |
dc.rights | Atribución 2.5 | * |
dc.rights | info:eu-repo/semantics/openAccess | spa |
dc.rights.uri | http://creativecommons.org/licenses/by/2.5/co/ | * |
dc.subject | Jatrophane Diterpenes | - |
dc.subject | Látex de euphorbia obtusifolia | - |
dc.subject | Actividad inhibitoria | - |
dc.subject | Cadena respiratoria mitocondrial | - |
dc.title | Jatrophane diterpenes from the latex of euphorbia obtusifolia with inhibitory activity on the mammalian mitochondrial respiratory chain | spa |
dc.type | info:eu-repo/semantics/article | spa |
dc.publisher.group | Infección y Cáncer | spa |
dc.identifier.doi | 10.1055/s-2003-37701 | - |
oaire.version | http://purl.org/coar/version/c_970fb48d4fbd8a85 | spa |
dc.rights.accessrights | http://purl.org/coar/access_right/c_abf2 | spa |
dc.identifier.eissn | 1439-0221 | - |
oaire.citationtitle | Planta Medica | spa |
oaire.citationstartpage | 177 | spa |
oaire.citationendpage | 178 | spa |
oaire.citationvolume | 69 | spa |
oaire.citationissue | 2 | spa |
dc.rights.creativecommons | https://creativecommons.org/licenses/by/4.0/ | spa |
dc.publisher.place | Stuttgart, Alemania | spa |
dc.type.coar | http://purl.org/coar/resource_type/c_2df8fbb1 | spa |
dc.type.redcol | https://purl.org/redcol/resource_type/ART | spa |
dc.type.local | Artículo de investigación | spa |
dc.description.researchgroupid | COL0012328 | spa |
dc.relation.ispartofjournalabbrev | Planta. Med. | spa |
Aparece en las colecciones: | Artículos de Revista en Ciencias Médicas |
Ficheros en este ítem:
Fichero | Descripción | Tamaño | Formato | |
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BetancurLiliana_2003_ JatrophaneDiterpenesLatex.pdf | Artículo de revista | 70.33 kB | Adobe PDF | Visualizar/Abrir |
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