Por favor, use este identificador para citar o enlazar este ítem: https://hdl.handle.net/10495/8524
Título : Ulososides and urabosides - Triterpenoid saponins from the caribbean marine sponge Ectyoplasia ferox
Autor : Colorado Ríos, Jhonny
Muñoz Lasso, Diana Carolina
Márquez Fernández, Diana Margarita
López Ortíz, Juan Bautista
Thomas, Oliver P.
Martínez Martínez, Alejandro
metadata.dc.subject.*: Saponinas
saponins
Esponjas
sponges
Esponja marina
Ectyoplasia ferox
Ulososidos
Urabósidos
http://aims.fao.org/aos/agrovoc/c_6795
http://aims.fao.org/aos/agrovoc/c_7321
Fecha de publicación : 2013
Editorial : MDPI
Citación : J. Colorado-Ríos, D. C. Muñoz-Lasso, D. M. Márquez-Fernández, M. E. Márquez-Fernández, J. B. López Ortíz, O. P. Thomas and A. Martínez-Martínez, "Ulososides and urabosides - Triterpenoid saponins from the caribbean marine sponge Ectyoplasia ferox," molecules, vol. 18, pp. 2598-2610, 2013.
Resumen : ABSTARCT: Three new triterpene glycosides, named ulososide F (1), urabosides A (2) and B (3), together with the previously reported ulososide A (4), were isolated from the Caribbean marine sponge Ectyoplasia ferox. Their structures were elucidated using extensive interpretation of 1D and 2D-NMR data, as well as HRESIMS. The aglycon of all compounds is a rare 30-norlonastane and the sugar residues were identified after acid hydrolysis and GC analyses. Cytotoxicities of the isolated compounds were evaluated against Jurkat and CHO cell lines by a MTT in vitro assay as well as a hemolysis assay. Unexpectedly, all these saponin derivatives showed very low activity in our bioassays.
ISSN : 1420-3049
metadata.dc.identifier.doi: 10.3390/molecules18032598
Aparece en las colecciones: Artículos de Revista en Farmacéutica

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