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https://hdl.handle.net/10495/29722| Título : | Comparison of Hybribio-H13 and Hybrid Capture 2 Human Papillomavirus tests for detection of CIN2+ and CIN3+ |
| Autor : | Agudelo Fernández, María Cecilia Torres González, Edmundo Agudelo, Samuel Ramírez Pineda, Arianis Tatiana Castañeda Vanegas, Kelly Melisa Kinslow, Connor J. Rodríguez Herrera, María Garland, Lisa Xie, Yi Orozco Castaño, Carlos Alberto Stoler, Mark Dean, Michael Sánchez Vásquez, Gloria |
| metadata.dc.subject.*: | Neoplasias del Cuello Uterino Uterine Cervical Neoplasms Papillomaviridae Hybribio, H13 Human Papillomavirus high-risk HPV testing Test validation |
| Fecha de publicación : | 2022 |
| Resumen : | RESUMEN: This study was carried out to compare the performance of the low-cost H13 test with HC2 to detect CIN2+ and CIN3+. Archived baseline samples tested by HC2 from women with biopsy-colposcopy directed diagnosis of CIN2+ (n=143) and CIN3+ (n=51) and 632 women with <CIN2, were retrospectively and blindly tested by H13. Relative sensitivity of H13 versus HC2 for detecting CIN2+ was 0.89 (90%CI,0.80-0.98; pni=0.66) and for CIN3+ was 0.92 (90%CI, 0.85-0.98; pni=0.35). Relative specificity was 1.19 (90% CI,1.05-1.33; pni<0.00001). In conclusion, H13 was as specific but less sensitive than HC2 for detecting CIN2+ or CIN3+. |
| Aparece en las colecciones: | Otros Materiales en Ciencias Médicas |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| BDD_H13_28-06-2018_Infeccionycancer.xlsx Restricted Access | Datos | 81.4 kB | Microsoft Excel XML | Visualizar/Abrir Request a copy |
| Request for Data Access.docx | Formato de solicitud | 65.67 kB | Microsoft Word XML | Visualizar/Abrir |
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