Por favor, use este identificador para citar o enlazar este ítem:
https://hdl.handle.net/10495/23931| Título : | Characterization of the venom of C. d. cumanesis of Colombia : Proteomic analysis and antivenomic study |
| Autor : | Quintana Castillo, Juan Carlos Vargas Muñoz, Leidy Johana Segura Latorre, Cesar Estrada Gómez, Sebastián Bueno Sánchez, Julio César Alarcón Pérez, Juan Carlos |
| metadata.dc.subject.*: | Venenos de Serpiente Snake Venoms Péptidos Peptides C. d. cumanensis venom HPLC-nESI-MS/MS |
| Fecha de publicación : | 2018 |
| Editorial : | MDPI |
| Resumen : | ABSTRACT: The Colombian rattlesnake Crotalus durissus cumanensis is distributed in three geographic zones of the country: the Atlantic Coast, the upper valley of the Magdalena River, and the eastern plains of the Colombian Orinoquía. Its venom induces neurological symptoms, such as eyelid ptosis, myasthenic facies, and paralysis of the respiratory muscles, which can lead to death. Identification and analysis of C. d. cumanensis showed nine groups of proteins responsible for the neurotoxic effect, of which the crotoxin complex was the most abundant (64.71%). Immunorecognition tests of C. d. cumanensis showed that the use of a commercial antivenom manufactured in Mexico resulted in immunoreactivity. |
| metadata.dc.identifier.eissn: | 2072-6651 |
| metadata.dc.identifier.doi: | 10.3390/toxins10020085 |
| Aparece en las colecciones: | Artículos de Revista en Farmacéutica y Alimentarias |
Ficheros en este ítem:
| Fichero | Descripción | Tamaño | Formato | |
|---|---|---|---|---|
| QuintanaJuan_2018_CharacterizationVenomCumanesisColombia.pdf | Artículo de investigación | 1.93 MB | Adobe PDF | Visualizar/Abrir |
Este ítem está sujeto a una licencia Creative Commons Licencia Creative Commons
